Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects.

作者: P. T. Fox , M. E. Raichle

DOI: 10.1073/PNAS.83.4.1140

关键词:

摘要: … Dynamic, physiological regulation of CBF by a mechanism (neuronal or biochemical) dependent on neuronal firing per se, but independent of the cerebral metabolic rate of oxygen, is …

参考文章(25)
Thomas Zeuthen, The Application of ion-selective microelectrodes Elsevier/North-Holland Biomedical Press , sole distributors for the U.S.A. and Canada, Elsevier/North-Holland Inc.. ,(1981)
Dietrich Werner Lübbers, Manfred Dietrich Kessler, Wilhelm Simon, Richard Pierson Buck, Helmut Acker, George Eisenman, Progress in Enzyme and Ion-Selective Electrodes ,(1981)
Jens Astrup, Dieter Heuser, Niels A. Lassen, Bengt Nilsson, Karin Norberg, Bo K. Siesjd, Evidence against H+ and K+ as main factors for the control of cerebral blood flow: a microelectrode study. Ciba Foundation symposium. pp. 313- 337 ,(1978) , 10.1002/9780470720370.CH16
D. W. Lubbers, E. Leniger-Follert, Capillary flow in the brain cortex during changes in oxygen supply and state of activation. Ciba Foundation symposium. pp. 21- 47 ,(1978) , 10.1002/9780470720370.CH4
M. E. Raichle, J. Markham, P. Herscovitch, W. R. W. Martin, M. A. Mintun, Brain blood flow measured with intravenous H2(15)O. II. Implementation and validation. The Journal of Nuclear Medicine. ,vol. 24, pp. 790- 798 ,(1983)
M. A. Mintun, M. E. Raichle, P. Herscovitch, W. R. W. Martin, Brain oxygen utilization measured with O-15 radiotracers and positron emission tomography The Journal of Nuclear Medicine. ,vol. 25, pp. 177- 187 ,(1984)
J. C. Baron, D. Rougemont, F. Soussaline, P. Bustany, C. Crouzel, M. G. Bousser, D. Comar, Local Interrelationships of Cerebral Oxygen Consumption and Glucose Utilization in Normal Subjects and in Ischemic Stroke Patients: A Positron Tomography Study Journal of Cerebral Blood Flow & Metabolism. ,vol. 4, pp. 140- 149 ,(1984) , 10.1038/JCBFM.1984.22
Rudolf Urbanics, Elfriede Leniger-Follert, Dietrich W. L�bbers, Time course of changes of extracellular H+ and K+ activities during and after direct electrical stimulation of the brain cortex Pfl�gers Archiv European Journal of Physiology. ,vol. 378, pp. 47- 53 ,(1978) , 10.1007/BF00581957