Prediction of acute myeloid leukaemia risk in healthy individuals

作者: Sagi Abelson , Grace Collord , Stanley WK Ng , Omer Weissbrod , Netta Mendelson Cohen

DOI: 10.1038/S41586-018-0317-6

关键词:

摘要: The incidence of acute myeloid leukaemia (AML) increases with age and mortality exceeds 90% when diagnosed after age 65. Most cases arise without any detectable early symptoms …

参考文章(48)
L Busque, R Mio, J Mattioli, E Brais, N Blais, Y Lalonde, M Maragh, DG Gilliland, Nonrandom X-Inactivation Patterns in Normal Females: Lyonization Ratios Vary With Age Blood. ,vol. 88, pp. 59- 65 ,(1996) , 10.1182/BLOOD.V88.1.59.BLOODJOURNAL88159
Tetsuichi Yoshizato, Bogdan Dumitriu, Kohei Hosokawa, Hideki Makishima, Kenichi Yoshida, Danielle Townsley, Aiko Sato-Otsubo, Yusuke Sato, Delong Liu, Hiromichi Suzuki, Colin O. Wu, Yuichi Shiraishi, Michael J. Clemente, Keisuke Kataoka, Yusuke Shiozawa, Yusuke Okuno, Kenichi Chiba, Hiroko Tanaka, Yasunobu Nagata, Takamasa Katagiri, Ayana Kon, Masashi Sanada, Phillip Scheinberg, Satoru Miyano, Jaroslaw P. Maciejewski, Shinji Nakao, Neal S. Young, Seishi Ogawa, Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia The New England Journal of Medicine. ,vol. 373, pp. 35- 47 ,(2015) , 10.1056/NEJMOA1414799
Terry M. Therneau, Patricia M. Grambsch, Modeling Survival Data: Extending the Cox Model ,(2000)
I. Martincorena, A. Roshan, M. Gerstung, P. Ellis, P. Van Loo, S. McLaren, D. C. Wedge, A. Fullam, L. B. Alexandrov, J. M. Tubio, L. Stebbings, A. Menzies, S. Widaa, M. R. Stratton, P. H. Jones, P. J. Campbell, High burden and pervasive positive selection of somatic mutations in normal human skin Science. ,vol. 348, pp. 880- 886 ,(2015) , 10.1126/SCIENCE.AAA6806
Andrew J. Vickers, Prediction models in cancer care CA: A Cancer Journal for Clinicians. ,vol. 61, pp. 315- 326 ,(2011) , 10.3322/CAAC.20118
Philip J Stephens, Patrick S Tarpey, Helen Davies, Peter Van Loo, Chris Greenman, David C Wedge, Serena Nik-Zainal, Sancha Martin, Ignacio Varela, Graham R Bignell, Lucy R Yates, Elli Papaemmanuil, David Beare, Adam Butler, Angela Cheverton, John Gamble, Jonathan Hinton, Mingming Jia, Alagu Jayakumar, David Jones, Calli Latimer, King Wai Lau, Stuart McLaren, David J McBride, Andrew Menzies, Laura Mudie, Keiran Raine, Roland Rad, Michael Spencer Chapman, Jon Teague, Douglas Easton, Anita Langerød, Oslo Breast Cancer Consortium (OSBREAC) Karesen Rolf 34 35 Schlichting Ellen 34 Naume Bjorn 35 36 Sauer Torill 35 37 Ottestad Lars 36, Ming Ta Michael Lee, Chen-Yang Shen, Benita Tan Kiat Tee, Bernice Wong Huimin, Annegien Broeks, Ana Cristina Vargas, Gulisa Turashvili, John Martens, Aquila Fatima, Penelope Miron, Suet-Feung Chin, Gilles Thomas, Sandrine Boyault, Odette Mariani, Sunil R Lakhani, Marc van de Vijver, Laura van ‘t Veer, John Foekens, Christine Desmedt, Christos Sotiriou, Andrew Tutt, Carlos Caldas, Jorge S Reis-Filho, Samuel AJR Aparicio, Anne Vincent Salomon, Anne-Lise Børresen-Dale, Andrea L Richardson, Peter J Campbell, P Andrew Futreal, Michael R Stratton, None, The landscape of cancer genes and mutational processes in breast cancer Nature. ,vol. 486, pp. 400- 404 ,(2012) , 10.1038/NATURE11017
Aaron M Newman, Scott V Bratman, Jacqueline To, Jacob F Wynne, Neville C W Eclov, Leslie A Modlin, Chih Long Liu, Joel W Neal, Heather A Wakelee, Robert E Merritt, Joseph B Shrager, Billy W Loo, Ash A Alizadeh, Maximilian Diehn, An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage Nature Medicine. ,vol. 20, pp. 548- 554 ,(2014) , 10.1038/NM.3519
Mingchao Xie, Charles Lu, Jiayin Wang, Michael D McLellan, Kimberly J Johnson, Michael C Wendl, Joshua F McMichael, Heather K Schmidt, Venkata Yellapantula, Christopher A Miller, Bradley A Ozenberger, John S Welch, Daniel C Link, Matthew J Walter, Elaine R Mardis, John F Dipersio, Feng Chen, Richard K Wilson, Timothy J Ley, Li Ding, Age-related mutations associated with clonal hematopoietic expansion and malignancies Nature Medicine. ,vol. 20, pp. 1472- 1478 ,(2014) , 10.1038/NM.3733
Barbara Deschler, Michael Lübbert, Acute myeloid leukemia: Epidemiology and etiology Cancer. ,vol. 107, pp. 2099- 2107 ,(2006) , 10.1002/CNCR.22233
Jan Krönke, Lars Bullinger, Veronica Teleanu, Florian Tschürtz, Verena I. Gaidzik, Michael W. M. Kühn, Frank G. Rücker, Karlheinz Holzmann, Peter Paschka, Silke Kapp-Schwörer, Daniela Späth, Thomas Kindler, Marcus Schittenhelm, Jürgen Krauter, Arnold Ganser, Gudrun Göhring, Brigitte Schlegelberger, Richard F. Schlenk, Hartmut Döhner, Konstanze Döhner, Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia Blood. ,vol. 122, pp. 100- 108 ,(2013) , 10.1182/BLOOD-2013-01-479188