Efficacy of follow-up after surgical treatment of colorectal liver metastases

作者: B.S. Langenhoff , P.F.M. Krabbe , T.J.M. Ruers

DOI: 10.1016/J.EJSO.2008.06.189

关键词:

摘要: PURPOSE: There is an increasing tendency for aggressive approach to colorectal liver metastases (CLM), even as second stage procedures after initial hepatic resection. This study assesses the efficacy of intensive follow-up resection CLM. PATIENTS AND METHODS: Hundred and three patients, operated on CLM, were followed disease recurrence. Outcome measures time imaging modality that revealed recurrence, performed treatment overall survival. RESULTS: After resection, 1- 3-year survival (OS) rates 91% 50%, disease-free 63% 45%. Seventy-four patients developed recurrent during follow-up. Resection recurrence was in 25 patients. OS this group 51 months. Patients with treated by chemotherapy had 34 In case 70% observed within 12 months, 92% 24 CT appeared be far a very useful surveillance modality, directing surgical 19 asymptomatic DISCUSSION: Follow-up CLM proves worthwhile, resulting meaningful re-operations quarter all underwent

参考文章(15)
Adson Ma, Ilstrup Dm, Fortner Jg, Daly Jm, Hughes Ks, Maclean Bj, Simon R, Foster Jh, Fitzherbert D, Songhorabodi S, Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of patterns of recurrence. Surgery. ,vol. 100, pp. 278- 284 ,(1986)
S. Connor, M.G. Hart, D.N. Redhead, H. Ireland, K.K. Madhavan, R.W. Parks, O.J. Garden, Follow-up and outcomes for resection of colorectal liver metastases in Edinburgh. Ejso. ,vol. 33, pp. 55- 60 ,(2007) , 10.1016/J.EJSO.2006.09.017
Bernard Nordlinger, Marguerite Guiguet, Jean-Christophe Vaillant, Pierre Balladur, Karim Boudjema, Philippe Bachellier, Daniel Jaeck, Association Française de Chirurgie, Surgical resection of colorectal carcinoma metastases to the liver: A prognostic scoring system to improve case selection, based on 1568 patients Cancer. ,vol. 77, pp. 1254- 1262 ,(1996) , 10.1002/(SICI)1097-0142(19960401)77:7<1254::AID-CNCR5>3.0.CO;2-I
Eddie K Abdalla, Jean-Nicolas Vauthey, Lee M Ellis, Vickie Ellis, Raphael Pollock, Kristine R Broglio, Kenneth Hess, Steven A Curley, None, Recurrence and Outcomes Following Hepatic Resection, Radiofrequency Ablation, and Combined Resection/Ablation for Colorectal Liver Metastases Annals of Surgery. ,vol. 239, pp. 818- 827 ,(2004) , 10.1097/01.SLA.0000128305.90650.71
Paul H. Sugarbaker, Repeat hepatectomy for colorectal metastases. Journal of Hepato-biliary-pancreatic Surgery. ,vol. 6, pp. 30- 38 ,(1999) , 10.1007/S005340050081
Vijay P. Khatri, Nicholas J. Petrelli, Jacques Belghiti, Extending the Frontiers of Surgical Therapy for Hepatic Colorectal Metastases: Is There a Limit? Journal of Clinical Oncology. ,vol. 23, pp. 8490- 8499 ,(2005) , 10.1200/JCO.2004.00.6155
Ren?? Adam, Val??rie Delvart, G??rard Pascal, Adrian Valeanu, Denis Castaing, Daniel Azoulay, Sylvie Giacchetti, Bernard Paule, Francis Kunstlinger, Odile Gh??mard, Francis Levi, Henri Bismuth, Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Annals of Surgery. ,vol. 240, pp. 644- 658 ,(2004) , 10.1097/01.SLA.0000141198.92114.F6
Harold J. Wanebo, Quyen D. Chu, Konstantine A. Avradopoulos, Michael P. Vezeridis, Current perspectives on repeat hepatic resection for colorectal carcinoma: A review Surgery. ,vol. 119, pp. 361- 371 ,(1996) , 10.1016/S0039-6060(96)80133-4
Yuman Fong, Joseph Fortner, Ruth L. Sun, Murray F. Brennan, Leslie H. Blumgart, Clinical Score for Predicting Recurrence After Hepatic Resection for Metastatic Colorectal Cancer: Analysis of 1001 Consecutive Cases Annals of Surgery. ,vol. 230, pp. 309- 321 ,(1999) , 10.1097/00000658-199909000-00004
Jim Cassidy, Josep Tabernero, Chris Twelves, René Brunet, Charles Butts, Thierry Conroy, Filippo Debraud, Arie Figer, Johannes Grossmann, Noriaki Sawada, Patrick Schöffski, Alberto Sobrero, Eric Van Cutsem, Eduardo Díaz-Rubio, XELOX (Capecitabine Plus Oxaliplatin): Active First-Line Therapy for Patients With Metastatic Colorectal Cancer Journal of Clinical Oncology. ,vol. 22, pp. 2084- 2091 ,(2004) , 10.1200/JCO.2004.11.069