Chemotherapy of advanced colorectal cancer
作者： Peter J. O’Dwyer , James P. Stevenson
DOI: 10.1007/978-1-4615-4977-2_5
关键词:
摘要: The development of 5-fluorouracil (5-FU) some 40 years ago was among the earliest events in field chemotherapy. Until recently, 5-FU remained only drug hundreds tested with reproducible activity colorectal cancer. Many elapsed before palliative benefit metastatic disease translated to a curative effect Dukes C and possibly B patients. This established paradigm cancer by which setting viewed as conferring survival or quality-of-life these patients, but most importantly laying groundwork for efficacy adjuvant therapy.
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