Utilizing RNA interference to enhance cancer drug discovery
作者： Christopher J. Lord , Nicholas Turner , Alan Ashworth
DOI: 10.1038/NRD2355
关键词:
摘要: With the development of RNA interference (RNAi) libraries, systematic and cost-effective genome-wide loss-of-function screens can now be carried out with aim assessing role specific genes in neoplastic phenotypes, rapid identification novel drug targets. Here, we discuss existing applications RNAi cancer discovery highlight areas this process that may benefit from technology future.
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