Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
作者： Hannah Farmer , Nuala McCabe , Christopher J. Lord , Andrew N. J. Tutt , Damian A. Johnson
DOI: 10.1038/NATURE03445
关键词:
摘要: … , suggesting that the damage induced is independent of BRCA function. Importantly, γ-H2AX … The formation of these foci is one hallmark of BRCA- dependent DSB repair, and the loss of …
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