Lobectomy After Induction Therapy for Stage IIIA NSCLC in the Presence of Persistent N2 Disease

摘要: Involvement of mediastinal nodes by metastatic deposits from non-small cell lung cancer (NSCLC) is characterized heterogeneous manifestations and diverse clinical scenarios (Table 11.1).1,2 For many these N2 subsets the therapeutic options are well known accepted in practice.3 Patients with potentially resectable disease detected preoperatively usually undergo induction treatment (chemotherapy and/or chemoradiotherapy) subsequent resection if they show a or pathological complete response.4 Conversely, patients technically unresectable NSCLC treated definitive chemoradiotherapy.5 When discovered only at final pathology, an adjuvant chemoradiation regimen proposed.4,5