Neuropsychiatric symptoms and caregiver's burden in Parkinson's disease.

摘要: Abstract Introduction In Parkinson's disease (PD), neuropsychiatric symptoms (NPS) can be particularly burdensome for caregivers. The main goal of this study was to assess the impact NPS, assessed by means a new specific scale, on caregiver burden. Methods A sample 584 pairs PD patients and their primary caregivers studied. Patients' NPS were measured with Scale Evaluation Neuropsychiatric Disorders in (SEND-PD), Zarit Caregiver Burden Inventory used quantify Three linear regression models built check factors associated burden, one total two subgroups stratified presence dementia. Results most frequent depression (in 66% sample), anxiety (65%) mental fatigue (57%). Patients dementia (n = 94; 16% sample) consistently presented more than without (p  Conclusions are highly determinants prevalent Detailed assessment interventions aimed at could alleviate