Changing paradigm of cancer therapy: precision medicine by next-generation sequencing
作者： William R. Wilcox , Yuan Xue
DOI: 10.28092/J.ISSN.2095-3941.2016.0003
关键词:
摘要: Precision medicine aims to identify the right drug, for patient, at dose, time, which is particularly important in cancer therapy. Problems such as variability of treatment response and resistance medication have been long-standing challenges oncology, especially development new medications. Solid tumors, unlike hematologic malignancies or brain are remarkably diverse their cellular origins developmental timing. The ability next-generation sequencing (NGS) analyze comprehensive landscape genetic alterations brings promises diseases that a highly complex heterogeneous composition cancer. Here we provide an overview how NGS able facilitate precision change paradigm therapy, solid through technical advancements, molecular diagnosis, monitoring clinical trials.
sci-hub.se 参考文章(38)
Daniel V.T. Catenacci, Andrea L. Amico, Sarah M. Nielsen, Daniel M. Geynisman, Brittany Rambo, George B. Carey, Cassandra Gulden, Jim Fackenthal, Robert D. Marsh, Hedy L. Kindler, Olufunmilayo I. Olopade, Tumor genome analysis includes germline genome: Are we ready for surprises? International Journal of Cancer. ,vol. 136, pp. 1559- 1567 ,(2015) , 10.1002/IJC.29128
X Chen, A Pappo, M A Dyer, Pediatric solid tumor genomics and developmental pliancy Oncogene. ,vol. 34, pp. 5207- 5215 ,(2015) , 10.1038/ONC.2014.474
Vidhya G. Krishnan, Philip J. Ebert, Jason C. Ting, Elaine Lim, Swee-Seong Wong, Audrey S.M. Teo, Yong G. Yue, Hui-Hoon Chua, Xiwen Ma, Gary S.L. Loh, Yuhao Lin, Joanna H.J. Tan, Kun Yu, Shenli Zhang, Christoph Reinhard, Daniel S.W. Tan, Brock A. Peters, Stephen E. Lincoln, Dennis G. Ballinger, Jason M. Laramie, Geoffrey B. Nilsen, Thomas D. Barber, Patrick Tan, Axel M. Hillmer, Pauline C. Ng, Whole-Genome Sequencing Of Asian Lung Cancers: Second-Hand Smoke Unlikely To Be Responsible for Higher Incidence Of Lung Cancer Among Asian Never-Smokers Cancer Research. ,vol. 74, pp. 6071- 6081 ,(2014) , 10.1158/0008-5472.CAN-13-3195
Nicola Waddell, Marina Pajic, Ann-Marie Patch, David K Chang, Karin S Kassahn, Peter Bailey, Amber L Johns, David Miller, Katia Nones, Kelly Quek, Michael CJ Quinn, Alan J Robertson, Muhammad ZH Fadlullah, Tim JC Bruxner, Angelika N Christ, Ivon Harliwong, Senel Idrisoglu, Suzanne Manning, Craig Nourse, Ehsan Nourbakhsh, Shivangi Wani, Peter J Wilson, Emma Markham, Nicole Cloonan, Matthew J Anderson, J Lynn Fink, Oliver Holmes, Stephen H Kazakoff, Conrad Leonard, Felicity Newell, Barsha Poudel, Sarah Song, Darrin Taylor, Nick Waddell, Scott Wood, Qinying Xu, Jianmin Wu, Mark Pinese, Mark J Cowley, Hong C Lee, Marc D Jones, Adnan M Nagrial, Jeremy Humphris, Lorraine A Chantrill, Venessa Chin, Angela M Steinmann, Amanda Mawson, Emily S Humphrey, Emily K Colvin, Angela Chou, Christopher J Scarlett, Andreia V Pinho, Marc Giry-Laterriere, Ilse Rooman, Jaswinder S Samra, James G Kench, Jessica A Pettitt, Neil D Merrett, Christopher Toon, Krishna Epari, Nam Q Nguyen, Andrew Barbour, Nikolajs Zeps, Nigel B Jamieson, Janet S Graham, Simone P Niclou, Rolf Bjerkvig, Robert Grützmann, Daniela Aust, Ralph H Hruban, Anirban Maitra, Christine A Iacobuzio-Donahue, Christopher L Wolfgang, Richard A Morgan, Rita T Lawlor, Vincenzo Corbo, Claudio Bassi, Massimo Falconi, Giuseppe Zamboni, Giampaolo Tortora, Margaret A Tempero, Royal North Shore Hospital Samra Jaswinder S. 39 Gill Anthony J. 39 Pavlakis Nick 39 Guminski Alex 39 Toon Christopher 39, Bankstown Hospital Asghari Ray 40 Merrett Neil D. 40 Pavey Darren 40 Das Amitabha 40, Liverpool Hospital Cosman Peter H. 41 Ismail Kasim 41 O’Connnor Chelsie 41, Westmead Hospital Lam Duncan McLeod Vincent W. 42 42 Pleass Henry C. 42 Richardson Arthur 42 James Virginia 42, Royal Prince Alfred Hospital Kench James G. 43 Cooper Caroline L. 43 Joseph David 43 Sandroussi Charbel 43 Crawford Michael 43 Gallagher James 43, Fremantle Hospital Texler Michael 44 Forest Cindy 44 Laycock Andrew 44 Epari Krishna P. 44 Ballal Mo 44 Fletcher David R. 44 Mukhedkar Sanjay 44, Sir Charles Gairdner Hospital Spry Nigel A. 45 DeBoer Bastiaan 45 Chai Ming 45, St John of God Healthcare Zeps Nikolajs 46 Beilin Maria 46 Feeney Kynan 46, Royal Adelaide Hospital Nguyen Nan Q. 47 Ruszkiewicz Andrew R. 47 Worthley Chris 47 Tan Chuan P. 47 Debrencini Tamara 47, Flinders Medical Centre Chen John 48 Brooke-Smith Mark E. 48 Papangelis Virginia 48, Greenslopes Private Hospital Tang Henry 49 Barbour Andrew P. 49, Envoi Pathology Clouston Andrew D. 50 Martin Patrick 50, Princess Alexandria Hospital O’Rourke Thomas J. 51 Chiang Amy 51 Fawcett Jonathan W. 51 Slater Kellee 51 Yeung Shinn 51 Hatzifotis Michael 51 Hodgkinson Peter 51, Austin Hospital Christophi Christopher 52 Nikfarjam Mehrdad 52 Mountain Angela 52, Victorian Cancer Biobank, Johns Hopkins Medical Institutes Eshleman James R. 54 Hruban Ralph H. 54 Maitra Anirban 54 Iacobuzio-Donahue Christine A. 54 Schulick Richard D. 54 Wolfgang Christopher L. 54 Morgan Richard A 54 Hodgin Mary 54, ARC-Net Centre for Applied Research on Cancer Scarpa Aldo 55 Lawlor Rita T. 55 Beghelli Stefania 55 Corbo Vincenzo 55 Scardoni Maria 55 Bassi Claudio 55, University of California, San Francisco Tempero Margaret A. 56, University of Glasgow Biankin Andrew V. 36 37 57 Grimmond Sean M. 37 38 Chang David K. 36 37 57 Musgrove Elizabeth A. 37 Jones Marc D. 36 37 Nourse Craig 37 38 Jamieson Nigel B. 37 57 Graham Janet S. 37 57, Greater Glasgow & Clyde National Health Service Biankin Andrew V. 36 37 57 Chang David K. 36 37 57 Jamieson Nigel B. 37 57 Graham Janet S. 37 57 Oien Karen 37 57 Hair Jane 57, None, Whole genomes redefine the mutational landscape of pancreatic cancer. Nature. ,vol. 518, pp. 495- 501 ,(2015) , 10.1038/NATURE14169
Ton N. Schumacher, Robert D. Schreiber, Neoantigens in cancer immunotherapy Science. ,vol. 348, pp. 69- 74 ,(2015) , 10.1126/SCIENCE.AAA4971
L. D. Wood, D. W. Parsons, S. Jones, J. Lin, T. Sjoblom, R. J. Leary, D. Shen, S. M. Boca, T. Barber, J. Ptak, N. Silliman, S. Szabo, Z. Dezso, V. Ustyanksky, T. Nikolskaya, Y. Nikolsky, R. Karchin, P. A. Wilson, J. S. Kaminker, Z. Zhang, R. Croshaw, J. Willis, D. Dawson, M. Shipitsin, J. K. V. Willson, S. Sukumar, K. Polyak, B. H. Park, C. L. Pethiyagoda, P. V. K. Pant, D. G. Ballinger, A. B. Sparks, J. Hartigan, D. R. Smith, E. Suh, N. Papadopoulos, P. Buckhaults, S. D. Markowitz, G. Parmigiani, K. W. Kinzler, V. E. Velculescu, B. Vogelstein, Genomic landscapes of human breast and colorectal cancers Science. ,vol. 318, pp. 1108- 1113 ,(2008) , 10.1126/SCIENCE.1145720
Xin An, Amit K. Tiwari, Yibo Sun, Pei-Rong Ding, Charles R. Ashby, Zhe-Sheng Chen, BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review. Leukemia Research. ,vol. 34, pp. 1255- 1268 ,(2010) , 10.1016/J.LEUKRES.2010.04.016
Catherine E. Cottrell, Hussam Al-Kateb, Andrew J. Bredemeyer, Eric J. Duncavage, David H. Spencer, Haley J. Abel, Christina M. Lockwood, Ian S. Hagemann, Stephanie M. O’Guin, Lauren C. Burcea, Christopher S. Sawyer, Dayna M. Oschwald, Jennifer L. Stratman, Dorie A. Sher, Mark R. Johnson, Justin T. Brown, Paul F. Cliften, Bijoy George, Leslie D. McIntosh, Savita Shrivastava, TuDung T. Nguyen, Jacqueline E. Payton, Mark A. Watson, Seth D. Crosby, Richard D. Head, Robi D. Mitra, Rakesh Nagarajan, Shashikant Kulkarni, Karen Seibert, Herbert W. Virgin, Jeffrey Milbrandt, John D. Pfeifer, Validation of a next-generation sequencing assay for clinical molecular oncology. The Journal of Molecular Diagnostics. ,vol. 16, pp. 89- 105 ,(2014) , 10.1016/J.JMOLDX.2013.10.002
Cassandra Willyard, 'Basket studies' will hold intricate data for cancer drug approvals Nature Medicine. ,vol. 19, pp. 655- 655 ,(2013) , 10.1038/NM0613-655
Anneli Dowler Nygaard, Karen-Lise Garm Spindler, Niels Pallisgaard, Rikke Fredslund Andersen, Anders Jakobsen, The prognostic value of KRAS mutated plasma DNA in advanced non-small cell lung cancer Lung Cancer. ,vol. 79, pp. 312- 317 ,(2013) , 10.1016/J.LUNGCAN.2012.11.016