Direct activation of guinea pig vagal afferent neurons by FMRFamide.

作者: Min-Goo Lee , Ji-Yong Park , Young Keun Park , Bradley J. Undem

DOI: 10.1097/WNR.0B013E3283495A6E

关键词:

摘要: Vagus nerve comprises two distinct kinds of nerves, nodose and jugular ganglionic nerves. We tested pharmacological difference between vagal nerves in the responsiveness to FMRFamide. The response probability FMRFamide was significantly higher than intracellular calcium measurement. Nodose also depolarized membrane potential more did, patch-clamp recording, although action discharge same both inward current induced by characterized as mixed cations. These results suggest that may act an activator modulator sensory for treating symptoms visceral diseases.

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