Myopathy during amiodarone treatment: a case report.
作者： F. Carella , E. Riva , L. Morandi , E. Cappiello , A. Mangoni
DOI: 10.1007/BF02333668
关键词:
摘要: The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and marked accumulation its metabolite desethylamiodarone was found in the sample despite normal blood levels. Amiodarone-induced morphological may be related to actual tissue concentration rather than level.
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W. Jacobson, J. M. Jacobs, M. F. Heath, F. R. Costa-Jussà, The induction of pulmonary phospholipidosis and the inhibition of lysosomal phospholipases by amiodarone British journal of experimental pathology. ,vol. 66, pp. 391- 397 ,(1985)
Robert B. Layzer, Neuromuscular manifestations of systemic disease Davis. ,(1984)
Martha E. Fedorko, James G. Hirsch, Zanvil A. Cohn, AUTOPHAGIC VACUOLES PRODUCED IN VITRO: II. Studies on the Mechanism of Formation of Autophagic Vacuoles Produced by Chloroquine Journal of Cell Biology. ,vol. 38, pp. 392- 402 ,(1968) , 10.1083/JCB.38.2.392
James J. Heger, Eric N. Prystowsky, Douglas P. Zipes, Relationships between amiodarone dosage, drug concentrations, and adverse side effects. American Heart Journal. ,vol. 106, pp. 931- 935 ,(1983) , 10.1016/0002-8703(83)90018-2
Martha E. Fedorko, James G. Hirsch, Zanvil A. Cohn, Autophagic Vacuoles Produced In Vitro: I. Studies on Cultured Macrophages Exposed to Chloroquine Journal of Cell Biology. ,vol. 38, pp. 377- 391 ,(1968) , 10.1083/JCB.38.2.377
M. E. Charness, F. Morady, M. M. Scheinman, Frequent neurologic toxicity associated with amiodarone therapy Neurology. ,vol. 34, pp. 669- 669 ,(1984) , 10.1212/WNL.34.5.669
G C Storey, P C Adams, R W Campbell, D W Holt, High-performance liquid chromatographic measurement of amiodarone and desethylamiodarone in small tissue samples after enzymatic digestion. Journal of Clinical Pathology. ,vol. 36, pp. 785- 789 ,(1983) , 10.1136/JCP.36.7.785
Aldo P. Maggioni, Angelo Maggi, Alberto Volpi, Vincenzo D'Aranno, Gianni Tognoni, Paolo Giani, Amiodarone distribution in human tissues after sudden death during Holter recording. American Journal of Cardiology. ,vol. 52, pp. 217- 218 ,(1983) , 10.1016/0002-9149(83)90104-2
Gregory D. Borowski, Catherine D. Garofano, Leslie I. Rose, Scott R. Spielman, Heschi R. Rotmensch, Allan M. Greenspan, Leonard N. Horowitz, Effect of long-term amiodarone therapy on thyroid hormone levels and thyroid function The American Journal of Medicine. ,vol. 78, pp. 443- 450 ,(1985) , 10.1016/0002-9343(85)90336-5
C. Meier, B. Kauer, U. M�ller, H. P. Ludin, Neuromyopathy during chronic amiodarone treatment. A case report. Journal of Neurology. ,vol. 220, pp. 231- 239 ,(1979) , 10.1007/BF00314147