Exosomes and diabetes
作者： Carlos Castaño , Anna Novials , Marcelina Párrizas
DOI: 10.1002/DMRR.3107
关键词:
摘要: Diabetes is a group of metabolic diseases characterized by elevated blood glucose levels that drive the development life-threatening complications. results from situation insufficient insulin action, either deficient production hormone pancreas, or resistance in peripheral tissues such as liver, muscle, adipose depots. Communication between organs thus central to maintenance homoeostasis. Recently, several studies are evidencing small vesicles called exosomes released by, amongst other, tissue can regulate gene expression other tissues, hence modulating interorgan crosstalk. Therefore, participate diabetes and its associated Their study holds potential providing us with novel biomarkers for early diagnosis stratification patients at risk developing diabetes, allowing timely implementation more personalized therapies. On hand, molecular dissection pathways initiated under situations stress could help gain deeper knowledge pathophysiology diseases.
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