Effect of adenosine on glucose metabolism of Rana ridibunda erythrocytes.
作者： Basile Michaelidis , Martha Kaloyianni , Katerina Moutou
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摘要: The effects of adenosine and inosine on Rana ridibunda erythrocyte metabolism were studied. Adenosine can be metabolized by erythrocytes as a carbon source for glycolysis to maintain ATP levels, whereas neither nor glucose could levels. rate lactate production was maximal (2.89 mumol ml-1 red cell h-1) in the presence together with compared that or alone. Inosine sustained similar did glucose. concentrations phosphorylated hexoses increased during 4 h incubation either without sodium iodoacetate accelerated loss ATP; furthermore, levels pyruvate significantly reduced inosine. Ouabain strongly inhibited formation adenosine, almost unchanged An inhibitor transport, dipyridamole, impeded increases concentration but not modify
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