Peroxisome proliferator-activated receptor γ and metabolic disease
作者： Timothy M. Willson , Millard H. Lambert , Steven A. Kliewer
DOI: 10.1146/ANNUREV.BIOCHEM.70.1.341
关键词:
摘要: … One of the most exciting discoveries has been identification of the nuclear hormone receptor called peroxisome proliferator–activated receptor γ (PPARγ), a transcription factor activated …
elsevier.com
sci-hub.se 参考文章(111)
I. Barroso, M. Gurnell, V. E. F. Crowley, M. Agostini, J. W. Schwabe, M. A. Soos, G. LI Maslen, T. D. M. Williams, H. Lewis, A. J. Schafer, V. K. K. Chatterjee, S. O'Rahilly, Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension Nature. ,vol. 402, pp. 880- 883 ,(1999) , 10.1038/47254
Ajay Chawla, Yaacov Barak, Laszlo Nagy, Debbie Liao, Peter Tontonoz, Ronald M. Evans, PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nature Medicine. ,vol. 7, pp. 48- 52 ,(2001) , 10.1038/83336
Jannet T. Huang, John S. Welch, Mercedes Ricote, Christoph J. Binder, Timothy M. Willson, Carolyn Kelly, Joseph L. Witztum, Colin D. Funk, Douglas Conrad, Christopher K. Glass, Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase Nature. ,vol. 400, pp. 378- 382 ,(1999) , 10.1038/22572
Samir S. Deeb, Lluis Fajas, Masami Nemoto, Jussi Pihlajamäki, Leena Mykkänen, Johanna Kuusisto, Markku Laakso, Wilfred Fujimoto, Johan Auwerx, A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nature Genetics. ,vol. 20, pp. 284- 287 ,(1998) , 10.1038/3099
J. L. Oberfield, J. L. Collins, C. P. Holmes, D. M. Goreham, J. P. Cooper, J. E. Cobb, J. M. Lenhard, E. A. Hull-Ryde, C. P. Mohr, S. G. Blanchard, D. J. Parks, L. B. Moore, J. M. Lehmann, K. Plunket, A. B. Miller, M. V. Milburn, S. A. Kliewer, T. M. Willson, A peroxisome proliferator-activated receptor γ ligand inhibits adipocyte differentiation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 6102- 6106 ,(1999) , 10.1073/PNAS.96.11.6102
Jean Himms‐Hagen, Brown adipose tissue thermogenesis: interdisciplinary studies The FASEB Journal. ,vol. 4, pp. 2890- 2898 ,(1990) , 10.1096/FASEBJ.4.11.2199286
Jin Jiang, Gary Struhl, Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb Nature. ,vol. 391, pp. 493- 496 ,(1998) , 10.1038/35154
Mercedes Ricote, Andrew C. Li, Timothy M. Willson, Carolyn J. Kelly, Christopher K. Glass, The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation Nature. ,vol. 391, pp. 79- 82 ,(1998) , 10.1038/34178
Dalei Shao, Shamina M. Rangwala, Shannon T. Bailey, Samuel L. Krakow, Mauricio J. Reginato, Mitchell A. Lazar, Interdomain communication regulating ligand binding by PPAR-γ Nature. ,vol. 396, pp. 377- 380 ,(1998) , 10.1038/24634
Rolf Thieringer, Judy E. Fenyk-Melody, Cheryl B. Le Grand, Beverly A. Shelton, Patricia A. Detmers, Elizabeth P. Somers, Linda Carbin, David E. Moller, Samuel D. Wright, Joel Berger, Activation of Peroxisome Proliferator-Activated Receptor γ Does Not Inhibit IL-6 or TNF-α Responses of Macrophages to Lipopolysaccharide In Vitro or In Vivo The Journal of Immunology. ,vol. 164, pp. 1046- 1054 ,(2000) , 10.4049/JIMMUNOL.164.2.1046