Role of Endometrial Autophagy in Physiological and Pathophysiological Processes.

摘要: Endometrium is the mucosal lining of uterus which expressed a cyclic process proliferation, secretion and scaling under control hormones secreted by ovary, it also plays an indispensable role in embryo implantation, constitution fetal-maternal interface, maintaining pregnancy. In pathophysiological conditions, abnormality or disorder endometrium may lead to endometrium-related diseases, such as endometriosis, hyperplasia even endometrial carcinoma. recent years, more evidence revealed that autophagy exists both stroma cells epithelial cells, activity changed different phases menstruation, well diseases. Here, we aim review level, regulatory factors function physiological endometria, discuss potential value target for therapies