Embracing sulfide and CO to understand nitric oxide biology

摘要: Research in the field of nitric oxide (NO) biology has come a long way from its humble beginnings as an ‘endothelium-dependent relaxing factor’ (EDRF) to ubiquitous cell messenger, modulator and regulator cellular activity it is recognized today. Those us who had good fortune witness development this research over years will remember moments where cross-talk NO with other biomolecules became central feature signalling process. Some you may even have similar “deja-vu” feeling we experienced while listening individual’s lecture at one those themed integrated physiology meetings. At occasion such meeting Glasgow 2010 two couldn’t help wondering why Sulfide appeared so when viewed through looking glass “hypoxic tolerance”. This Editorial serves explain Nitric Oxide Society Board Members’ decision expand scope our “house journal” include chemistry molecules, most feel timely justified evolved.