Prevalence of nocturnal hypoglycemia in first trimester of pregnancy in patients with insulin treated diabetes mellitus.

作者: ELLINOR HELLMUTH , PETER DAMM , LARS MØLSTED-PEDERSEN , INGER BENDTSON

DOI: 10.1034/J.1600-0412.2000.079011958.X

关键词:

摘要: Background. Excellent metabolic control before conception and during diabetic pregnancies is the aim in order to avoid malformations perinatal morbidity. Since an inverse correlation between median blood glucose concentration (BG) hypoglycemia as well a high prevalence of nocturnal have been described, we investigated frequency predictive value bedtime for development this condition insulin treated patients.Methods. During hospitalization, with no other changes patients' normal schedules, hourly samples were drawn from iv-cannula 22.00 h 07.00 one night. BG (venous whole blood) hemoglobin A1c determined following day.Results. Fifty-three patients participated; subsequently ten excluded due discontinuation sampling night, caused by either discomfort or cannula problems. Of remaining 43 patients, 16 (37%) had at least blood...

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