Trypanosoma brucei RRM1 Is a Nuclear RNA-Binding Protein and Modulator of Chromatin Structure

作者: Arunasalam Naguleswaran , Kapila Gunasekera , Bernd Schimanski , Manfred Heller , Andrew Hemphill

DOI: 10.1128/MBIO.00114-15

关键词:

摘要: … next-generation sequencing (RIP-Seq). Enrichment ratios were … Read densities of samples from RIP-Seq with HA-RRM1 (R) … For each example, the scales for R (RIP-Seq) and I (input) …

参考文章(72)
S. Kramer, R. Queiroz, L. Ellis, H. Webb, J. D. Hoheisel, C. Clayton, M. Carrington, Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2α phosphorylation at Thr169 Journal of Cell Science. ,vol. 121, pp. 3002- 3014 ,(2008) , 10.1242/JCS.031823
K Ziegelbauer, P Overath, Identification of invariant surface glycoproteins in the bloodstream stage of Trypanosoma brucei. Journal of Biological Chemistry. ,vol. 267, pp. 10791- 10796 ,(1992) , 10.1016/S0021-9258(19)50088-6
E. Pays, H. Coquelet, P. Tebabi, A. Pays, D. Jefferies, M. Steinert, E. Koenig, R. O. Williams, I. Roditi, Trypanosoma brucei: constitutive activity of the VSG and procyclin gene promoters. The EMBO Journal. ,vol. 9, pp. 3145- 3151 ,(1990) , 10.1002/J.1460-2075.1990.TB07512.X
Laure Twyffels, Cyril Gueydan, Véronique Kruys, Shuttling SR proteins: more than splicing factors. FEBS Journal. ,vol. 278, pp. 3246- 3255 ,(2011) , 10.1111/J.1742-4658.2011.08274.X
G. Rudenko, D. Bishop, K. Gottesdiener, L.H. Van der Ploeg, Alpha-amanitin resistant transcription of protein coding genes in insect and bloodstream form Trypanosoma brucei. The EMBO Journal. ,vol. 8, pp. 4259- 4263 ,(1989) , 10.1002/J.1460-2075.1989.TB08611.X
Martin Wurst, Beate Seliger, Bhaskar Anand Jha, Cornelia Klein, Rafael Queiroz, Christine Clayton, Expression of the RNA recognition motif protein RBP10 promotes a bloodstream‐form transcript pattern in Trypanosoma brucei Molecular Microbiology. ,vol. 83, pp. 1048- 1063 ,(2012) , 10.1111/J.1365-2958.2012.07988.X
Gabriela Schumann Burkard, Sandro Käser, Patrícia Rosa de Araújo, Bernd Schimanski, Arunasalam Naguleswaran, Sebastian Knüsel, Manfred Heller, Isabel Roditi, Nucleolar proteins regulate stage-specific gene expression and ribosomal RNA maturation inTrypanosoma brucei Molecular Microbiology. ,vol. 88, pp. 827- 840 ,(2013) , 10.1111/MMI.12227
Ian D Manger, John C Boothroyd, Identification of a nuclear protein in Trypanosoma brucei with homology to RNA-binding proteins from cis-splicing systems. Molecular and Biochemical Parasitology. ,vol. 97, pp. 1- 11 ,(1998) , 10.1016/S0166-6851(98)00118-2
Pegine B. Walrad, Paul Capewell, Katelyn Fenn, Keith R. Matthews, The post-transcriptional trans-acting regulator, TbZFP3, co-ordinates transmission-stage enriched mRNAs in Trypanosoma brucei Nucleic Acids Research. ,vol. 40, pp. 2869- 2883 ,(2012) , 10.1093/NAR/GKR1106