Unique magnetic signatures of mismatched base pairs in DNA
作者： Vadim Apalkov , Julia Berashevich , Tapash Chakraborty
DOI: 10.1063/1.3328877
关键词:
摘要: Magnetic properties of DNA containing mispairs, such as different conformations the G⋅A mispair, or a G⋅T mispair inserted into chain, have been theoretically investigated. The essential ingredients for these studies, charge transfer integrals, were evaluated from sequences and optimized in solvent. We find that magnetic susceptibilities host chain large number Watson–Crick base pairs are significantly altered presence effects depend on choice mispairs. In particular, insertion even single changes nature magnetization (sign susceptibility) DNA. propose measurement might provide direct route to detection identification those
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sci-hub.se 参考文章(17)
DNA damage recognition CRC Press. ,(2005) , 10.1201/9780849352683
Charge Migration in DNA Charge Migration in DNA: Perspectives from Physics, Chemistry, and Biology, NanoScience and Technology. ,(2007) , 10.1007/978-3-540-72494-0
S. Nakamae, M. Cazayous, A. Sacuto, P. Monod, H. Bouchiat, Intrinsic low temperature paramagnetism in B-DNA. Physical Review Letters. ,vol. 94, pp. 248102- ,(2005) , 10.1103/PHYSREVLETT.94.248102
R. Peierls, Zur Theorie des Diamagnetismus von Leitungselektronen European Physical Journal. ,vol. 80, pp. 763- 791 ,(1933) , 10.1007/BF01342591
Vadim Apalkov, Tapash Chakraborty, Influence of correlated electrons on the paramagnetism of DNA Physical Review B. ,vol. 78, pp. 104424- ,(2008) , 10.1103/PHYSREVB.78.104424
Kittusamy Senthilkumar, Ferdinand C. Grozema, Célia Fonseca Guerra, F. Matthias Bickelhaupt, Frederick D. Lewis, Yuri A. Berlin, Mark A. Ratner, Laurens D. A. Siebbeles, Absolute Rates of Hole Transfer in DNA Journal of the American Chemical Society. ,vol. 127, pp. 14894- 14903 ,(2005) , 10.1021/JA054257E
Tomáš Kubař, Marcus Elstner, What governs the charge transfer in DNA? The role of DNA conformation and environment. Journal of Physical Chemistry B. ,vol. 112, pp. 8788- 8798 ,(2008) , 10.1021/JP803661F
H. R. Drew, R. M. Wing, T. Takano, C. Broka, S. Tanaka, K. Itakura, R. E. Dickerson, Structure of a B-DNA dodecamer: conformation and dynamics. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 78, pp. 2179- 2183 ,(1981) , 10.1073/PNAS.78.4.2179
Juyeon Yi, Emergent paramagnetism of DNA molecules Physical Review B. ,vol. 74, pp. 212406- ,(2006) , 10.1103/PHYSREVB.74.212406
F. Fixe, V. Chu, D.M.F. Prazeres, J.P. Conde, Single base mismatch detection by microsecond voltage pulses. Biosensors and Bioelectronics. ,vol. 21, pp. 888- 893 ,(2005) , 10.1016/J.BIOS.2005.02.011