Signaling dynamics and peroxisomes
作者： Fred D Mast , Richard A Rachubinski , John D Aitchison
DOI: 10.1016/J.CEB.2015.05.002
关键词:
摘要: Peroxisomes are remarkably responsive organelles. Their composition, abundance and even their mechanism of biogenesis influenced strongly by cell type the environment. This plasticity underlies peroxisomal functions in metabolism detoxification dangerous reactive oxygen species. However, peroxisomes integrated into cellular system as a whole such that they communicate intimately with other organelles, control signaling dynamics case innate immune responses to infectious disease, contribute processes fundamental longevity. The increasing evidence for having roles various organismal functions, combined malleability, suggests complex mechanisms operate specificity extending well beyond peroxisome itself. A deeper understanding could offer opportunities exploiting changes function.
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