Innate and Adaptive Immune Response to Fungal Products and Allergens

摘要: Exposure to fungi and their products is practically ubiquitous, yet most of this little consequence healthy individuals. This because there are a number elaborate mechanisms deal with these exposures. Most designed recognize neutralize such However, in understanding it has become clear that many them overlap our ability respond disruptions tissue function caused by trauma or deterioration. These responses involve the innate adaptive immune systems usually through activation nuclear factor kappa B production cytokines considered inflammatory accompanied other factors can moderate reactivities. Depending on different genetic backgrounds extent mechanisms, various pathologies resulting symptoms ensue. Complicating fact bias toward type 2 responses. Thus, understand what we refer as allergens from fungal sources, must first how they influence mechanisms. In doing so proteins described essentially homologues own signal cause disruptions.