DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.

作者: Xue Zhang , Jing Han , Li Feng , Lianghui Zhi , Da Jiang

DOI: 10.1093/CARCIN/BGAA056

关键词:

摘要: … Furthermore, the wound scratch assay was also carried out, and it was revealed that the … -DUOX2 and sh-Control stably infected HCT116 and HT-29 cells. More than 90% of these cells …

参考文章(40)
Hui Cao, Enping Xu, Hong Liu, Ledong Wan, Maode Lai, Epithelial–mesenchymal transition in colorectal cancer metastasis: A system review Pathology - Research and Practice. ,vol. 211, pp. 557- 569 ,(2015) , 10.1016/J.PRP.2015.05.010
Jiajun Wang, Miaomiao Shao, Min Liu, Peike Peng, Lili Li, Weicheng Wu, Lan Wang, Fangfang Duan, Mingming Zhang, Shushu Song, Dongwei Jia, Yuanyuan Ruan, Jianxin Gu, PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma. Biochemical and Biophysical Research Communications. ,vol. 463, pp. 839- 845 ,(2015) , 10.1016/J.BBRC.2015.06.021
Helmut Grasberger, Jun Gao, Hiroko Nagao-Kitamoto, Sho Kitamoto, Min Zhang, Nobuhiko Kamada, Kathryn A. Eaton, Mohamad El-Zaatari, Andrew B. Shreiner, Juanita L. Merchant, Chung Owyang, John Y. Kao, Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine. Gastroenterology. ,vol. 149, pp. 1849- 1859 ,(2015) , 10.1053/J.GASTRO.2015.07.062
Michael W. Klymkowsky, Pierre Savagner, Epithelial-Mesenchymal Transition The American Journal of Pathology. ,vol. 174, pp. 1588- 1593 ,(2009) , 10.2353/AJPATH.2009.080545
Rong Wang, Wan-Mohaiza Dashwood, Hui Nian, Christiane V. Löhr, Kay A. Fischer, Naoto Tsuchiya, Hitoshi Nakagama, Hassan Ashktorab, Roderick H. Dashwood, NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). International Journal of Cancer. ,vol. 128, pp. 2581- 2590 ,(2011) , 10.1002/IJC.25610
Ravi K. Amaravadi, Transcriptional regulation of autophagy in RAS-driven cancers Journal of Clinical Investigation. ,vol. 125, pp. 1393- 1395 ,(2015) , 10.1172/JCI81504
Yongzhong Wu, Smitha Antony, Agnes Juhasz, Jiamo Lu, Yun Ge, Guojian Jiang, Krishnendu Roy, James H. Doroshow, Up-regulation and Sustained Activation of Stat1 Are Essential for Interferon-γ (IFN-γ)-induced Dual Oxidase 2 (Duox2) and Dual Oxidase A2 (DuoxA2) Expression in Human Pancreatic Cancer Cell Lines Journal of Biological Chemistry. ,vol. 286, pp. 12245- 12256 ,(2011) , 10.1074/JBC.M110.191031
Francesca De Amicis, Carmela Guido, Marta Santoro, Marilena Lanzino, Salvatore Panza, Paola Avena, Maria Luisa Panno, Ida Perrotta, Saveria Aquila, Sebastiano Andò, A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells Journal of Cellular and Molecular Medicine. ,vol. 18, pp. 2252- 2265 ,(2014) , 10.1111/JCMM.12363
YONGHZONG WU, SMITHA ANTONY, STEPHEN M. HEWITT, GUOJIAN JIANG, SHERRY X. YANG, JENNIFER L. MEITZLER, AGNES JUHASZ, JIAMO LU, HAN LIU, JAMES H. DOROSHOW, KRISHNENDU ROY, Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody. International Journal of Oncology. ,vol. 42, pp. 1229- 1238 ,(2013) , 10.3892/IJO.2013.1821
Sylvia Luxen, Steven A. Belinsky, Ulla G. Knaus, Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer. Cancer Research. ,vol. 68, pp. 1037- 1045 ,(2008) , 10.1158/0008-5472.CAN-07-5782