Molecular steps of cell suicide: an insight into immune senescence.

作者: Sudhir Gupta

DOI: 10.1023/A:1006653917314

关键词:

摘要: The cellular and molecular basis of immune senescence is unclear. A number mechanisms have been proposed. In this issue the Journal Clinical Immunology, some for various immunologic abnormalities in aging are presented. article, steps both death receptor mitochondrial pathways apoptosis general reviewed. particular, role T-cell discussed.

参考文章(137)
Stanislava S. Stosic-Grujicic, Miodrag L. Lukic, The Production of TNF, IL-1 And IL-6 in Cutaneous Tissues During Maturation and Aging Advances in Experimental Medicine and Biology. pp. 411- 414 ,(1995) , 10.1007/978-1-4615-1941-6_86
Quinn L. Deveraux, Henning R. Stennicke, Guy S. Salvesen, John C. Reed, Endogenous inhibitors of caspases. Journal of Clinical Immunology. ,vol. 19, pp. 388- 398 ,(1999) , 10.1023/A:1020502800208
Aggarwal Bb, Natarajan K, Tumor necrosis factors: developments during the last decade. European Cytokine Network. ,vol. 7, pp. 93- 124 ,(1996)
S. Papa, V. P. Skulachev, Reactive oxygen species, mitochondria, apoptosis and aging. Molecular and Cellular Biochemistry. ,vol. 174, pp. 305- 319 ,(1997) , 10.1007/978-1-4615-6111-8_47
Nigel J. Waterhouse, Douglas R. Green, Mitochondria and apoptosis: HQ or high-security prison? Journal of Clinical Immunology. ,vol. 19, pp. 378- 387 ,(1999) , 10.1023/A:1020550716138
Marilyn L. Thoman, D. N. Ernst, M. V. Hobbs, W. O. Weigle, T Cell Differentiation and Functional Maturation in Aging Mice Advances in Experimental Medicine and Biology. ,vol. 330, pp. 93- 106 ,(1993) , 10.1007/978-1-4615-2926-2_8
T Hennet, C Richter, E Peterhans, Tumour necrosis factor-α induces superoxide anion generation in mitochondria of L929 cells Biochemical Journal. ,vol. 289, pp. 587- 592 ,(1993) , 10.1042/BJ2890587
Pramod C. Rath, Bharat B. Aggarwal, TNF-induced signaling in apoptosis. Journal of Clinical Immunology. ,vol. 19, pp. 350- 364 ,(1999) , 10.1023/A:1020546615229
Alessandra Bettinardi, Duilio Brugnoni, Eugenia Quiròs-Roldan, Alberto Malagoli, Stefania La Grutta, Antonio Correra, Luigi D. Notarangelo, Missense Mutations in the Fas Gene Resulting in Autoimmune Lymphoproliferative Syndrome: A Molecular and Immunological Analysis Blood. ,vol. 89, pp. 902- 909 ,(1997) , 10.1182/BLOOD.V89.3.902