Evaluation and Treatment for Older Men with Elevated PSA

作者: Benjamin H. Press , Marc A. Bjurlin , Samir S. Taneja

DOI: 10.1007/978-3-319-78646-9_2

关键词:

摘要: The management of elderly men presenting with asymptomatic, elevated PSA levels requires careful consideration the risks and benefits biopsy, cancer detection, subsequent treatment. In over age 75 years, levels, prevalence prostate is high, but benefit treatment not clear. risk mortality declines as competing grow. As such, patient health longevity mainstay decision-making in this clinical scenario. If healthy, further evaluation MRI, predictive nomograms, and/or selective biomarkers may allow selection at greatest harboring cancers which potentially affect natural longevity. manner, all 76 modestly will require those few who remain might still from early detection.

参考文章(114)
Chorneyko A, Dhillon K, St Onge J, Verma A, PSA density improves prediction of prostate cancer. Canadian Journal of Urology. ,vol. 21, pp. 7312- 7321 ,(2014)
L. K. Heilbrun, W. A. Sakr, D. J. Grignon, J. D. Crissman, J. J.E. Pontes, B. J. Cassin, G. P. Haas, High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: an autopsy study of 249 cases. in Vivo. ,vol. 8, pp. 439- 444 ,(1994)
Marc A. Bjurlin, James S. Wysock, Samir S. Taneja, Optimization of Prostate Biopsy Urologic Clinics of North America. ,vol. 41, pp. 299- 313 ,(2014) , 10.1016/J.UCL.2014.01.011
Xiaosong Meng, Andrew B. Rosenkrantz, Neil Mendhiratta, Michael Fenstermaker, Richard Huang, James S. Wysock, Marc A. Bjurlin, Susan Marshall, Fang-Ming Deng, Ming Zhou, Jonathan Melamed, William C. Huang, Herbert Lepor, Samir S. Taneja, Relationship Between Prebiopsy Multiparametric Magnetic Resonance Imaging (MRI), Biopsy Indication, and MRI-ultrasound Fusion–targeted Prostate Biopsy Outcomes European Urology. ,vol. 69, pp. 512- 517 ,(2016) , 10.1016/J.EURURO.2015.06.005
Neil Mendhiratta, Andrew B. Rosenkrantz, Xiaosong Meng, James S. Wysock, Michael Fenstermaker, Richard Huang, Fang-Ming Deng, Jonathan Melamed, Ming Zhou, William C. Huang, Herbert Lepor, Samir S. Taneja, Magnetic Resonance Imaging-Ultrasound Fusion Targeted Prostate Biopsy in a Consecutive Cohort of Men with No Previous Biopsy: Reduction of Over Detection through Improved Risk Stratification. The Journal of Urology. ,vol. 194, pp. 1601- 1606 ,(2015) , 10.1016/J.JURO.2015.06.078
Ghassan A Barayan, Fadi Brimo, Louis R Bégin, James A Hanley, Zhihui Liu, Wassim Kassouf, Armen G Aprikian, Simon Tanguay, None, Factors influencing disease progression of prostate cancer under active surveillance: a McGill University Health Center cohort. BJUI. ,vol. 114, ,(2014) , 10.1111/BJU.12754
Soo Borson, James M. Scanlan, Peijun Chen, Mary Ganguli, The Mini‐Cog as a Screen for Dementia: Validation in a Population‐Based Sample Journal of the American Geriatrics Society. ,vol. 51, pp. 1451- 1454 ,(2003) , 10.1046/J.1532-5415.2003.51465.X
Katharina Braun, Daniel D. Sjoberg, Andrew J. Vickers, Hans Lilja, Anders S. Bjartell, A Four-kallikrein Panel Predicts High-grade Cancer on Biopsy: Independent Validation in a Community Cohort European Urology. ,vol. 69, pp. 505- 511 ,(2016) , 10.1016/J.EURURO.2015.04.028
Michael W. Kattan, Thomas M. Wheeler, Peter T. Scardino, Postoperative Nomogram for Disease Recurrence After Radical Prostatectomy for Prostate Cancer Journal of Clinical Oncology. ,vol. 17, pp. 1499- 1499 ,(1999) , 10.1200/JCO.1999.17.5.1499