The essential JIL-1 kinase regulates histone H3 phosphorylation and maintains chromatin structure in Drosophila
作者： Weiguo Zhang
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摘要: vi CHAPTER 1. GENERAL INTRODUCTION 1 DISSERTATION ORGANIZATION BACKGROUND 2 RESEARCH QUESTIONS AND SIGNIFICANCE 3 2. LITERATURE REVIEW 7 CHROMATIN STRUCTURE ATP-DEPENDENT REMODELING 12 HISTONE MODIFICATION 14 DOSAGE COMPENSATION IN DROSOPHILA MELANOGASTER 18 3. THE JIL-1 TANDEM KINASE MEDIATES H3 PHOSPHORYLATION IS REQUIRED FOR MAINTENANCE OF 24 SUMMARY RESULTS 27 DISCUSSION 34 EXPERIMENTAL PROCEDURES 37 ACKNOWLEDGMENTS 41 REFERENCES FIGURE LEGENDS 46 TABLES FIGURES 50 4. GENETIC PHENOTYPIC ANALYSIS ALLELES CHROMOSOMAL REVEALS A FUNC TIONAL REQUIREMENT AT MULTIPLE DEVELOPMENTAL STAGES 57 ABSTRACT 58 MATERIALS METHODS 59 63
sci-hub.st 参考文章(151)
J Müller, Mariann Bienz, None, Sharp anterior boundary of homeotic gene expression conferred by the fushi tarazu protein. The EMBO Journal. ,vol. 11, pp. 3653- 3661 ,(1992) , 10.1002/J.1460-2075.1992.TB05450.X
J. Simon, M. Peifer, W. Bender, M. O'Connor, Regulatory elements of the bithorax complex that control expression along the anterior-posterior axis. The EMBO Journal. ,vol. 9, pp. 3945- 3956 ,(1990) , 10.1002/J.1460-2075.1990.TB07615.X
Asifa Akhtar, Daniele Zink, Peter B. Becker, Chromodomains are protein–RNA interaction modules Nature. ,vol. 407, pp. 405- 409 ,(2000) , 10.1038/35030169
Laurent Kuras, Kevin Struhl, Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme Nature. ,vol. 399, pp. 609- 613 ,(1999) , 10.1038/21239
Richard J. Lin, Laszlo Nagy, Satoshi Inoue, Wenlin Shao, Wilson H. Miller, Ronald M. Evans, Role of the histone deacetylase complex in acute promyelocytic leukaemia Nature. ,vol. 391, pp. 811- 814 ,(1998) , 10.1038/35895
V MELLER, M KURODA, Sex and the single chromosome. Advances in Genetics. ,vol. 46, pp. 1- 24 ,(2002) , 10.1016/S0065-2660(02)46002-6
David Lane, Ed Harlow, Antibodies: A Laboratory Manual ,(1988)
Dan L Lindsley, Georgianna G. Zimm, The Genome of Drosophila Melanogaster ,(1992)
James A Kennison, Introduction to Trx-G and Pc-G Genes Chromatin and Chromatin Remodeling Enzymes, Part C. ,vol. 377, pp. 61- 70 ,(2003) , 10.1016/S0076-6879(03)77003-7
Christophe Dhalluin, Justin E. Carlson, Lei Zeng, Cheng He, Aneel K. Aggarwal, Ming-Ming Zhou, Ming-Ming Zhou, Structure and ligand of a histone acetyltransferase bromodomain Nature. ,vol. 399, pp. 491- 496 ,(1999) , 10.1038/20974