Investigation of household contacts of pulmonary tuberculosis patients increases case detection in Mwanza City, Tanzania.

摘要: Tuberculosis (TB) contact tracing is a key strategy for containing TB and provides addition to the passive case finding approach. However, this practice has not been implemented in Tanzania, where there unacceptably high treatment gap of 62.1% between cases estimated detected. Therefore calls more aggressive close gap. We aimed determine magnitude predictors bacteriologically-confirmed pulmonary among household contacts index city Mwanza, Tanzania. This study was carried out from August December 2016 Mwanza at outpatient clinics Tertiary Hospital Bugando Medical Centre, Sekou-Toure Regional Hospital, Nyamagana District Hospital. Bacteriologically-confirmed diagnosed May July were identified laboratory registers book. Contacts traced by home visits nurses, data collected using standardized screening questionnaire. To detect bacterioriologically-confirmed TB, two sputum samples per under supervision all following standard operating procedures. Samples transported Centre investigation fluorescent smear microscopy, GeneXpert MTB/RIF Lowenstein–Jensen (LJ) culture. Logistic regression used contacts. During period, 456 93 TB identified. Among these contacts, 13 (2.9%) positive, 18 (3.9%) MTB-culture positive four (0.9%) AFB-smear positive. Overall, 29 (6.4%) had TB. Predictors were7being married (Odds ratio [OR], 3.3; 95% confidence interval [CI], 1.4–8.0; p = 0.012) consuming less than three meals day (OR, 3.7; CI, 1.6–8.7; p = 0.009). Our suggest that seven 100 living same house with patient develop These results therefore underscore need implement routine control tuberculosis burden countries such as