MIF/MAF-Macrophage Interactions: Biochemical Characterization of a Putative Glycolipid Receptor for MIF and the Existence and Properties of Two Distinct MIFs
作者： J. R. David , H. G. Remold , T. J. Higgins , D. Y. Liu , W. H. Churchill
DOI: 10.1007/978-94-009-8793-7_20
关键词:
摘要: A lymphocyte mediator of cellular immunity, the migration inhibition factor (MIF), alters behaviour macrophages (David 1966; Bloom & Bennett 1966). Studies so far indicate that MIF is biochemically indistinguishable from macrophage activating (MAF), a modulates morphology, biochemistry, and function macrophages, enhancing their microbicidal tumoricidal capabilities (Nathan et al. 1973; David Remold 1976). Thus, one important mechanism for activation through mediators (MIF/MAF).
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