Predictive Value of Platelet Indices in Development of Preeclampsia
作者： Rashmi Jain , Monica Soni , Rekha Choudhary , Shaifali Dadhich , Sudesh Agrawal
DOI: 10.5005/JP-JOURNALS-10006-1164
关键词:
摘要: Aim: To evaluate the association between changes in platelet indices (platelet count, mean volume, distribution width) and development of preeclampsia. Materials methods: Two hundred pregnant women at 20 to 24 weeks gestation with singleton pregnancy normal blood pressure were enrolled after taking well-informed consent. At monthly intervals CBC (complete count) was done from till 40 7 days delivery. Data regarding increasing collected analyzed. Results: Platelet count decreased significantly patients preeclampsia compared (19.4% vs 7.4%). Mean volume increased (44.5% 9.22%). Increase PDW observed (47.19% 29.4%). Conclusion: Patients are more likely have significant decrease increase MPV. These can be an earlier gestational age than rise BP directly proportional progressive hypertension. Thus, estimation considered as early, simple cost-effective procedure assessment severity
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sci-hub.st 参考文章(17)
Pradhan Bb, Satpathy Uk, Mohanty A, Pattnaik, Mohapatra S, Platelet estimation: its prognostic value in pregnancy induced hypertension. Indian journal of physiology and pharmacology. ,vol. 51, pp. 160- ,(2007)
JM Roberts, DW Cooper, Pathogenesis and genetics of pre-eclampsia. The Lancet. ,vol. 357, pp. 53- 56 ,(2001) , 10.1016/S0140-6736(00)03577-7
Elvany Verônica dos Santos, José Meirelles Filho, Plaquetograma em gestantes normais e com pré-eclâmpsia Revista Brasileira de Ginecologia e Obstetrícia. ,vol. 26, pp. 201- 206 ,(2004) , 10.1590/S0100-72032004000300005
James J. Walker, Alan D. Cameron, Steingrimur Bjornsson, Charles R.J. Singer, Carol Fraser, Can platelet volume predict progressive hypertensive disease in pregnancy American Journal of Obstetrics and Gynecology. ,vol. 161, pp. 676- 679 ,(1989) , 10.1016/0002-9378(89)90378-5
Steven G. Tygart, Dennis K. McRoyan, Joseph A. Spinnato, Cheryl J. McRoyan, David Z. Kitay, Longitudinal study of platelet indices during normal pregnancy American Journal of Obstetrics and Gynecology. ,vol. 154, pp. 883- 887 ,(1986) , 10.1016/0002-9378(86)90476-X
Yusuf Ahmed, Basil Iddekinge, Carolyn Paul, Mark H. F. Sullivan, Murdoch G. Elder, Retrospective analysis of platelet numbers and volumes in normal pregnancy and in pre-eclampsia. British Journal of Obstetrics and Gynaecology. ,vol. 100, pp. 216- 220 ,(1993) , 10.1111/J.1471-0528.1993.TB15233.X
Yusuf Ahmed, Basil van Iddekinge, Carolyn Paul, Mark HF Sullivan, Murdoch G Elder, None, Retrospective analysis of platelet numbers and volumes in normal pregnancy and in pre-eclampsia International Journal of Gynecology & Obstetrics. ,vol. 43, pp. 230- 230 ,(1993) , 10.1016/0020-7292(93)90342-T
S. Hernandez-Diaz, S. Toh, S. Cnattingius, Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study. BMJ. ,vol. 338, ,(2009) , 10.1136/BMJ.B2255
Xu Xiong, William D. Fraser, Nestor N. Demianczuk, History of abortion, preterm, term birth, and risk of preeclampsia: A population-based study American Journal of Obstetrics and Gynecology. ,vol. 187, pp. 1013- 1018 ,(2002) , 10.1067/MOB.2002.126282
Ozgur Dundar, Pinar Yoruk, Levent Tutuncu, Alev Akyol Erikci, Murat Muhcu, Ali Rustu Ergur, Vedat Atay, Ercument Mungen, Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsia Prenatal Diagnosis. ,vol. 28, pp. 1052- 1056 ,(2008) , 10.1002/PD.2126