Bacteriocins from Lactic Acid Bacteria: A Review of Biosynthesis, Mode of Action, Fermentative Production, Uses, and Prospects

摘要: Bacteriocins are antimicrobial peptides that help bacteria fight competing in microecological systems. of lactic acid (LAB) have attracted much interest recent years because their properties make them suitable as natural food preservatives against specific pathogens, and possible supplement to antibiotics drug resistant bacterial strains. LAB bacteriocins generally classified into the lantibiotics non-lantibiotics, latter divided four subgroups. To date, only nisin a lesser extent, pediocin commercially applied for use. Clinical applications still limited animal health. One more exciting prospects on use is possibility subjecting bioengineering either increase activity or further specify target microorganism. The would it less damaging gut microflora, which common drawback conventional antibiotic therapy. This paper focuses nature, biology, based knowledge gained abroad Philippines during last two decades. Keywords—lactic bacteria, peptides, bacteriocin, bacteriocin application, biosynthesis,