Plasma Ascorbic Acid Levels and G-6-PD Activities in Symptomatic, Asymptomatic Malaria and Malaria Negative Subjects

摘要: Malaria parasite endemicity and development have been associated with ascorbic acid availability the activity of G-6-PD. There is no record studies that relate two parameters in malaria subjects. Plasma levels glucose-6-phosphate dehydrogenase (G-6-PD) symptomatic malaria, asymptomatic negative subjects Calabar Municipality were measured to evaluate relationship. The level (2.22±1.82m/dl) was significantly lower (P<0.05) than control (3.47±0.97mg/dl). However, (2.22 ± 1.82 mg/dl) (P<0.05). G-6-PD activities positive subjects, (asymptomatic, 12.75 6.2U/gHb 18.5 6.1U/gHb) higher (8.34 6.6U/gHb, P<0.05). G-6-PD/ascorbic ratios non-malaria (2.40), (3.73), (8.33) differed A correlations observed between (r =0.444, p<0.05), while a correlation = 0.239, These results show an inverse relationship G-6-PD/Ascorbic differentiate non-malaria, malaria. Both vary status parasitaemia. From these finding we advice should be interpreted relation endemic zones.