Graphene Oxide: A Smart (Starting) Material for Natural Methylxanthines Adsorption and Detection.

摘要: Natural methylxanthines, caffeine, theophylline and theobromine, are widespread biologically active alkaloids in human nutrition, found mainly beverages (coffee, tea, cocoa, energy drinks, etc.). Their detection is thus of extreme importance, many studies devoted to this topic. During the last decade, graphene oxide (GO) reduced (RGO) gained popularity as constituents sensors (chemical, electrochemical biosensors) for methylxanthines. The main advantages GO RGO with respect easiness cheapness synthesis, notable higher solubility polar solvents (water, among others), reactivity towards these targets (mainly due π–π interactions); one disadvantages lower electrical conductivity, especially when using them sensors. Nonetheless, their use becoming more common, obtainment very good results terms selectivity sensitivity (up 5.4 × 10−10 mol L−1 1.8 10−9 caffeine theophylline, respectively). Moreover, ability protect DNA RNA from enzymatic digestion renders it best candidates biosensors based on nucleic acids. This an up-to-date review