Impact of age on survival of locoregional nasopharyngeal carcinoma: An analysis of the Surveillance, Epidemiology, and End Results program database, 2004-2013.

摘要: Objectives To determine the impact of age at diagnosis and other factors on survival in nasopharyngeal carcinoma (NPC). Design, setting participants A retrospective, population-based cohort study 3103 patients are selected, whose records were submitted to Surveillance, Epidemiology, End Results (SEER) database between 2004 2013. We evaluated demographic clinical characteristics who 20 years or older with a primary, non-metastatic NPC. Main outcome measures Overall (OS) risks OS NPC-specific survival. rates 1, 3, 5 85.8%, 71.0%, 62.6%, respectively. Older was significant predictor poor OS, as Chinese ethnicity. also determined that middle-aged white patients, but not black higher risk death than younger same race/ethnicity. Nodal (N) stage 0-1 disease when comparing N0-1 vs N2-3 disease. Finally, we found married had decreased compared those single. Conclusions The NPC is inferior patients. Race/ethnicity, marital status, important modifiers risk. Collectively, our results indicate management requires optimisation.