BDNF levels in adipose tissue and hypothalamus were reduced in mice with MSG-induced obesity
作者： Yong Jun Jin , Peng Juan Cao , Wei Hua Bian , Ming E. Li , Rong Zhou
DOI: 10.1179/1476830515Y.0000000039
关键词:
摘要: Objectives: To observe the expression of brain-derived neurotrophic factor (BDNF) in hypothalamic and adipose tissue mice with monosodium glutamate (MSG)-induced obesity.Methods: The effects lesions, specifically arcuate nucleus (ARC) induced by MSG injection were studied male ICR at neonatal stage. following parameters compared: body weight, length, Lee's index, food intake, temperature, fat levels total cholesterol (CHOL), triglyceride (TG), low-density lipoprotein (LDL), high-density (HDL), blood glucose (GLU). BDNF measured using western blotting.Results: Compared control group, model group had significantly higher CHOL, TG, LDL, HDL, GLU levels. markedly down-regulated group.Discussion: may be closely ass...
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