Using brown adipose tissue to treat obesity – the central issue

摘要: Current therapeutic strategies are proving inadequate to deal with growing obesity rates because of the inherent resistance human body weight loss. The activation brown adipose tissue (BAT) represents an opportunity increase energy expenditure and loss alongside improved lipid glucose homeostasis. Research into regulation BAT has made increasing thermogenic capacity individual treat metabolic disease a plausible strategy, despite thermogenesis being under tight central nervous system control. Previous therapies targeted at sympathetic have had deleterious effects lack organ specificity, but advances in our understanding regulatory systems might open up better specifically stimulate obese individuals aid reduction.