A sensitive high-throughput method to detect activating mutations of Jak2 in peripheral-blood samples.
作者： Martin Sattler , Christoph Walz , Brian J. Crowley , Eva Lengfelder , Pasi A. Jänne
DOI: 10.1182/BLOOD-2005-07-2899
关键词:
摘要: An activating mutation of the Jak2 tyrosine kinase (V617F) is commonly detected in polycythemia vera (65%-97%),[1][1]-[6][2] essential thrombocythemia (23%-57%),[1][1],[2][3],[4][4]-[6][2] and idiopathic myelofibrosis (35%-57%)[1][1],[2][3],[4][4]-[6][2] as well at low percentages other
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