Competition between Two Pathways for Sugar Uptake by the Phosphoenolpyruvate‐Dependent Sugar Phosphotransferase System in Salmonella typhimurium
作者： Bob J. SCHOLTE , Pieter W. POSTMA
DOI: 10.1111/J.1432-1033.1981.TB06171.X
关键词:
摘要: The interaction between the two pathways for glucose entry via phosphoenolpyruvate: sugar phosphotransferase system, i.e. enzyme II-A/II-B and enzymes II-BGlc/IIIGlc, was studied in Salmonella typhimurium. Thio-β-d-glucoside 5-thio-d-glucose were shown to be substrates of P-pyruvate: specific II-BGlc both intact cells toluene-treated S. activity pathway strongly inhibited by presence substrates. It is concluded that compete phosphoryl groups provided P-pyruvate, under conditions tested flow through I/HPr rate-limiting step vivo studied. results corroborate proposed mechanism regulatory function system which predicts a net dephosphorylation components substrate P-pyruvate : phosphotransferase.
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