Hypoxic stress upregulates Kir2.1 expression by a pathway including hypoxic-inducible factor-1α and dynamin2 in brain capillary endothelial cells

作者: Hideto Yamamura , Yoshiaki Suzuki , Hisao Yamamura , Kiyofumi Asai , Wayne Giles

DOI: 10.1152/AJPCELL.00154.2017

关键词:

摘要: Brain capillary endothelial cells (BCECs) play a central role in maintenance of blood-brain barrier (BBB) function and, therefore, are essential for nervous system homeostasis and integrity...

参考文章(55)
Robert E. Ten Eick, David W. Whalley, Helge H. Rasmussen, Connections: heart disease, cellular electrophysiology, and ion channels. The FASEB Journal. ,vol. 6, pp. 2568- 2580 ,(1992) , 10.1096/FASEBJ.6.8.1375569
S Engelhardt, S Patkar, O O Ogunshola, Cell-specific blood-brain barrier regulation in health and disease: a focus on hypoxia. British Journal of Pharmacology. ,vol. 171, pp. 1210- 1230 ,(2014) , 10.1111/BPH.12489
Kim A. Dora, Christopher J. Garland, Properties of smooth muscle hyperpolarization and relaxation to K+ in the rat isolated mesenteric artery American Journal of Physiology-heart and Circulatory Physiology. ,vol. 280, ,(2001) , 10.1152/AJPHEART.2001.280.6.H2424
C. W. Leffler, J. S. Smith, J. L. Edrington, S. L. Zuckerman, H. Parfenova, Mechanisms of hypoxia-induced cerebrovascular dilation in the newborn pig American Journal of Physiology-heart and Circulatory Physiology. ,vol. 272, ,(1997) , 10.1152/AJPHEART.1997.272.3.H1323
Miaomiao Chang, Hua Du, Fang Wang, Lili Jiang, Jing Zhao, Ling Hai, Yonghong Shi, Gaowa Sharen, Down-regulation of hypoxia-inducible factor-1 suppresses malignant biological behavior of triple-negative breast cancer cells International Journal of Clinical and Experimental Medicine. ,vol. 7, pp. 3933- 3940 ,(2014)
Sanja Sever, Joann Chang, Changkyu Gu, Dynamin rings: not just for fission. Traffic. ,vol. 14, pp. 1194- 1199 ,(2013) , 10.1111/TRA.12116
Hong Cao, Shaun Weller, James D. Orth, Jing Chen, Bing Huang, Ji-Long Chen, Mark Stamnes, Mark A. McNiven, Actin and Arf1-dependent recruitment of a cortactin–dynamin complex to the Golgi regulates post-Golgi transport Nature Cell Biology. ,vol. 7, pp. 483- 492 ,(2005) , 10.1038/NCB1246
Hyung Gyun Kim, Yong Pil Hwang, Hye Gwang Jeong, Metallothionein-III induces HIF-1α-mediated VEGF expression in brain endothelial cells Biochemical and Biophysical Research Communications. ,vol. 369, pp. 666- 671 ,(2008) , 10.1016/J.BBRC.2008.02.059
Hiroaki Kito, Daiju Yamazaki, Susumu Ohya, Hisao Yamamura, Kiyofumi Asai, Yuji Imaizumi, Up-regulation of K(ir)2.1 by ER stress facilitates cell death of brain capillary endothelial cells. Biochemical and Biophysical Research Communications. ,vol. 411, pp. 293- 298 ,(2011) , 10.1016/J.BBRC.2011.06.128
Arlek M. González-Jamett, Fanny Momboisse, Valentina Haro-Acuña, Jorge A. Bevilacqua, Pablo Caviedes, Ana María Cárdenas, Dynamin-2 Function and Dysfunction Along the Secretory Pathway Frontiers in Endocrinology. ,vol. 4, pp. 126- 126 ,(2013) , 10.3389/FENDO.2013.00126