Phospholipids having antimicrobial activity with or without the presence of antimicrobials
作者： Maryjane Utley , Karen A. Krogfelt , Paul S. Cohen , David C. Laux
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摘要: Phospholipids (e.g. MPPA and DPPS) show a remarkable antimicrobial effect against gram negative Pseudomonas Klebsiella) positive Staphylococcus Enterococcus) bacteria. When the phospholipids are combined with antibiotics ampicillin, ceftazidime, or piperacillin) of antibiotic is enhanced by presence phospholipid. The substance invention will be used alone in combination antibiotics, antimicrobials, antifungal, antiviral, antiprotozoal drugs for combat infectious diseases, such as prophylactic, cytocidal, antibacterial, bacteriostatic, and/or bacteriocidal effects.
google.co.in 参考文章(55)
Hans Krause, Georgios Samonis, Elias J. Anaissie, Gerald P. Bodey, Pharmaceutical formulations: liposomes incorporating aromatic polyene antibiotics ,(1988)
Simo Tarpila, Anneli Kivinen, Phospholipid composition and use thereof ,(1993)
R.B. Sykes, A. Morris, Resistance of Pseudomonas aeruginosa to antimicrobial drugs. Progress in Medicinal Chemistry. ,vol. 12, pp. 333- 393 ,(1975) , 10.1016/S0079-6468(08)70180-2
P. Elsbach, J. Weiss, R.C. Franson, S. Beckerdite-Quagliata, A. Schneider, L. Harris, Separation and purification of a potent bactericidal/permeability-increasing protein and a closely associated phospholipase A2 from rabbit polymorphonuclear leukocytes. Observations on their relationship. Journal of Biological Chemistry. ,vol. 254, pp. 11000- 11009 ,(1979) , 10.1016/S0021-9258(19)86622-X
Andrew S. Janoff, Pieter R. Cullis, Lois E. Bolcsak, Lawrence D. Mayer, Marcel B. Bally, Liposomes comprising aminoglycoside phosphates and methods of production and use ,(1993)
Bo Nilsson, Howard C. Krivan, Clifford A. Lingwood, Use of host cell phospholipids for inhibiting microbial colonization ,(1991)
M.H. Richmond, R.B. Sykes, The β-Lactamases of Gram-Negative Bacteria and their Possible Physiological Role Advances in Microbial Physiology. ,vol. 9, pp. 31- 88 ,(1973) , 10.1016/S0065-2911(08)60376-8
W A Woodruff, R E Hancock, Construction and characterization of Pseudomonas aeruginosa protein F-deficient mutants after in vitro and in vivo insertion mutagenesis of the cloned gene. Journal of Bacteriology. ,vol. 170, pp. 2592- 2598 ,(1988) , 10.1128/JB.170.6.2592-2598.1988
Hans G. BOMAN, Ingrid FAYE, Gudmundur H. GUDMUNDSSON, Jong-Youn LEE, Dan-Anders LIDHOLM, Cell-free immunity in Cecropia FEBS Journal. ,vol. 201, pp. 23- 31 ,(1991) , 10.1111/J.1432-1033.1991.TB16252.X
Anthony G. Gristina, Girish Giridhar, Particle induced amplification of immune response ,(1995)