Fostering synergy between cell biology and systems biology
作者： James A. Eddy , Cory C. Funk , Nathan D. Price
DOI: 10.1016/J.TCB.2015.04.005
关键词:
摘要: In the shared pursuit of elucidating detailed mechanisms cell function, systems biology presents a natural complement to ongoing efforts in biology. Systems aims characterize biological through integrated and quantitative modeling cellular information. The process model building analysis provides value synthesizing cataloging information about cells molecules, predicting identifying generalizable themes, generating hypotheses guiding experimental design, highlighting knowledge gaps refining understanding. turn, incorporating domain expertise data is crucial for towards whole models. An iterative cycle interaction between biologists advances goals both fields establishes framework mechanistic understanding genome-to-phenome relationship.
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