Increasing memory load modulates regional brain activity in older adults as measured by fMRI.
作者： Jeffrey R. Petrella , Brent A. Townsend , Amishi P. Jha , Lauretta A. Ziajko , Melissa J. Slavin
DOI: 10.1176/JNP.17.1.75
关键词:
摘要: Several recent studies using functional magnetic resonance imaging (fMRI) during recognition memory tests have suggested that the ability to neuromodulate as a function of cognitive demand may be impaired in older adults due age-related cell loss and neural volume reduction specific regions. In current study, (ages 59-77) were tested with fMRI delayed-recognition task which load for faces was varied across trials. Activity greater amplitude three- versus one-face stimuli within superior, middle, inferior frontal gyri, intraparietal sulcus, fusiform gyrus. It concluded modulate activity increasing is preserved despite reductions volume.
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