Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses

摘要: Colletotrichum species are fungal pathogens that devastate crop plants worldwide. Host infection involves the differentiation of specialized cell types associated with penetration, growth inside living host cells (biotrophy) and tissue destruction (necrotrophy). We report here genome transcriptome analyses higginsianum infecting Arabidopsis thaliana graminicola maize. Comparative genomics showed both fungi have large sets pathogenicity-related genes, but families genes encoding secreted effectors, pectin-degrading enzymes, secondary metabolism transporters peptidases expanded in C. higginsianum. Genome-wide expression profiling revealed these transcribed successive waves linked to pathogenic transitions: effectors enzymes induced before penetration during biotrophy, whereas most hydrolases upregulated later, at switch necrotrophy. Our findings show preinvasion perception plant-derived signals substantially reprograms gene indicate previously unknown functions for particular types.