Tissue Guided Regeneration with Platelet Rich Plasma and Resorptive Collagen Membrane in Case of Chronic Osteomyelitis of Tibia

摘要: Background: Chronic osteomyelitis is a serious and difficult complication in open fractures, occurring about 20% of cases. Treatment approach must be multidisciplinary with surgical basis. At the end classical eradication infection, there often large bone defect. Guided tissue regeneration (GTR) allogeneic platelet gel, autologous cancellous graft resorptive collagen membrane one possibilities how to bridge Patients: 26 year old male patient, suffered from chronic osteomyelitis. The therapy for was started after two months healed, soft defect grafted surralis flap. GTR gel performed fill Results: essential idea this combine healing capacities platelet-derived growth factors osteogenic stem cells modeling capacity gel. After 4 incorporated, fully bridged full weight-bearing achieved. Using membrane, increased. Conclusions: aim our treatment approach, by combined can improve shorten outcome.