Functionality, antibacterial efficiency and biocompatibility of nanosilver/chitosan/silk/ phosphate scaffolds 1. Synthesis and optimization of nanosilver/chitosan matrices through gamma rays irradiation and their antibacterial activity
作者： Wafa I Abdel-Fattah , Abdel Sattar M Sallam , Nagwa A Atwa , E Salama , Ahmed M Maghraby
DOI: 10.1088/2053-1591/1/3/035024
关键词:
摘要: Silver nanoparticles (SN) were synthesized via the green approach of gamma radiation. Chitosan was used as both reducing and stabilizing agent. Studies involved influence various parameters four irradiation doses three silver precursor concentrations on produced nanoparticles. The UV–vis spectra proved characteristic surface plasmon resonance (SPR) SN whose intensities positions dependant concentrations. X-ray diffraction analyses transmission electron microscopy (TEM) observations fabrication spherical crystalline face centered cubic with a mean diameter 7–22 nm. Further characterization fabricated nanoparticles/chitosan composite (SNCC) conducted using Fourier transform infrared spectroscopy zeta potential measurements. Finally, bactericidal effect SNCC glutaraldehyde tested against different medically relevant strains gram negative positive bacteria. Excellent selective inhibiting function films by strain compared to other ones. synthesis successful size selection obtained through reduction nitrate chitosan protective agent achieved presenting high functions, especially for strain.
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