The effects of raloxifene and simvastatin on plasma lipids and endothelium.

作者: Eftihia Sbarouni , Panagiota Flevari , Christos Kroupis , Zenon S. Kyriakides , Katerina Koniavitou

DOI: 10.1023/A:1027391405600

关键词:

摘要: Purpose: Raloxifene is a selective estrogen receptor modulator and an attractive alternative to replacement as it obviates the need for progestin does not increase C-reactive protein levels. We compared effects of simvastatin raloxifene treatments on lipid profile, levels adhesion molecules endothelium dependent independent vasoreactivity.

参考文章(46)
Writing Group for the Women's Health Initiative Investigators, Writing Group for the Women's Health Initiative Investigators, None, Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial JAMA. ,vol. 288, pp. 321- 333 ,(2002) , 10.1001/JAMA.288.3.321
Eric H Lieberman, Marie D Gerhard, Akimi Uehata, Brian W Walsh, Andrew P Selwyn, Peter Ganz, Alan C Yeung, Mark A Creager, Estrogen Improves Endothelium-Dependent, Flow-Mediated Vasodilation in Postmenopausal Women Annals of Internal Medicine. ,vol. 121, pp. 936- 941 ,(1994) , 10.7326/0003-4819-121-12-199412150-00005
Shih-Jen Hwang, Christie M. Ballantyne, A. Richey Sharrett, Louis C. Smith, Clarence E. Davis, Antonio M. Gotto, Eric Boerwinkle, Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: The Atherosclerosis Risk In Communities (ARIC) study Circulation. ,vol. 96, pp. 4219- 4225 ,(1997) , 10.1161/01.CIR.96.12.4219
Teresa Caulin-Glaser, William J Farrell, Steven E Pfau, Barry Zaret, Katherine Bunger, John F Setaro, Joseph J Brennan, Jeffrey R Bender, Michael W Cleman, Henry S Cabin, Michael S Remetz, Modulation of Circulating Cellular Adhesion Molecules in Postmenopausal Women With Coronary Artery Disease Journal of the American College of Cardiology. ,vol. 31, pp. 1555- 1560 ,(1998) , 10.1016/S0735-1097(98)00145-4
E.S.G. Stroes, H.A. Koomans, T.J. Rabelink, T.W.A. de Bruin, Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication. The Lancet. ,vol. 346, pp. 467- 471 ,(1995) , 10.1016/S0140-6736(95)91322-X
Maria A Sardo, Maria Castaldo, Maurizio Cinquegrani, Michele Bonaiuto, Antonella Maesano, Filippo Schepis, Maria C Zema, Giuseppe M Campo, Francesco Squadrito, Antonino Saitta, Effects of simvastatin treatment on sICAM-1 and sE-selectin levels in hypercholesterolemic subjects Atherosclerosis. ,vol. 155, pp. 143- 147 ,(2001) , 10.1016/S0021-9150(00)00520-7
Brian W Walsh, David A Cox, Andreas Sashegyi, Robert A Dean, Russell P Tracy, Pamela W Anderson, Role of tumor necrosis factor-α and interleukin-6 in the effects of hormone replacement therapy and raloxifene on C-reactive protein in postmenopausal women The American Journal of Cardiology. ,vol. 88, pp. 825- 828 ,(2001) , 10.1016/S0002-9149(01)01865-3
Pierre D. Delmas, Nina H. Bjarnason, Bruce H. Mitlak, Anne-Catherine Ravoux, Aarti S. Shah, William J. Huster, Michael Draper, Claus Christiansen, Effects of Raloxifene on Bone Mineral Density, Serum Cholesterol Concentrations, and Uterine Endometrium in Postmenopausal Women New England Journal of Medicine. ,vol. 337, pp. 1641- 1647 ,(1997) , 10.1056/NEJM199712043372301