Nutritional and physiologic significance of human milk proteins

摘要: Human milk contains a wide variety of proteins that contribute to its unique qualities. Many these are digested and provide well-balanced source amino acids rapidly growing infants. Some proteins, such as bile salt-stimulated lipase, amylase, beta-casein, lactoferrin, haptocorrin, alpha1-antitrypsin, assist in the digestion utilization micronutrients macronutrients from milk. Several with antimicrobial activity, immunoglobulins, kappa-casein, lysozyme, alpha-lactalbumin, lactoperoxidase, relatively resistant against proteolysis gastrointestinal tract may, intact or partially form, defense breastfed infants pathogenic bacteria viruses. Prebiotic promotion growth beneficial Lactobacilli Bifidobacteria, may also be provided by human proteins. This type activity can limit several pathogens decreasing intestinal pH. peptides have immunomodulatory activities (eg, cytokines lactoferrin), whereas others insulin-like factor, epidermal lactoferrin) likely involved development mucosa other organs newborns. In combination, breast-milk providing adequate nutrition while simultaneously aiding infection facilitating optimal important physiologic functions