Antigen mimotopes and vaccine against cancerous diseases
作者： Erika Jensen-Jarolim , Christoph Zielinski , Otto Scheiner , Hubert Pehamberger , Heimo Breiteneder
DOI:
关键词:
摘要: The invention relates to a vaccine against cancers and antigen mimotopes that are associated with the high molecular weight melanoma (HMW-MAA). immunologically detected by monoclonal HMW-MAA 225.28S antibody comprise at least one peptide having length of 6 14 amino acids. inventive allows for an active immunization (HMW-MAA) has both prophylactic therapeutical effects. can also be used assay immune response achieved.
lens.org 参考文章(9)
Soldano Ferrone, Anti-idiotype antibodies to anti-human high molecular weight-melanoma associated antigen. ,(1989)
S. Ferrone, X. Wang, Active Specific Immunotherapy of Malignant Melanoma and Peptide Mimics of the Human High-Molecular-Weight Melanoma-Associated Antigen Recent results in cancer research. ,vol. 158, pp. 231- 235 ,(2001) , 10.1007/978-3-642-59537-0_23
Mary L. Disis, Martin A. Cheever, Methods for eliciting or enhancing reactivity to HER-2/neu protein ,(1996)
Mary L. Disis, Martin A. Cheever, Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated ,(1995)
Robert M. Hudziak, Brian M. Fendly, H. Michael Shepard, Axel Ullrich, Monoclonal antibodies directed to the HER2 receptor ,(1995)
H. Voshol, D. Schultz, C. Garcia-Echeverria, A. Le Cardinal, M. Geiser, Identification of the Human Melanoma-associated Chondroitin Sulfate Proteoglycan Antigen Epitope Recognized by the Antitumor Monoclonal Antibody 763.74 from a Peptide Phage Library Cancer Research. ,vol. 59, pp. 905- 910 ,(1999)
Soldano Ferrone, Peptide mimics useful for treating disease ,(1998)
Soldano Ferrone, Ashwani K. Sood, Xin-Hui Wang, Induction of a strong immune response to a self-tumor associated antigen ,(2000)
Ferrone S, Wang X, Luo W, Immunotherapy of melanoma: peptide mimics of a human high molecular weight-melanoma associated antigen. Medicina-buenos Aires. pp. 48- 50 ,(2000)