Magnetic Resonance Studies of Membranes and Lipids

摘要: To relate the structure of a membrane to its functional properties at molecular level requires techniques define detailed organization components, and identify components involved in specific function intact membrane. Both problems are complicated by multiplicity components. The use X-ray diffraction spatial relationships has been dynamic motion lipids absence high degree order proteins, so that patterns contain only limited structural information. nuclear magnetic resonance (NMR) electron spin (ESR) more appropriate for structure, which both their average distance interaction can, principle, be defined. underlying assumption this approach is assembly into imposes mutual steric restrictions on will expressed as characteristic pattern motion. Since there also good evidence proteins number membranes have precise lipid requirements, it would expected impose with they interact.