作者: Thomas E. Weldon , Mark S. Soloway
DOI: 10.1016/0090-4295(75)90367-2
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摘要: This study sought to determine whether or not transitional carcinoma cells can adhere and progressively grow on normal inflamed bladder urothelium. Inflammation was produced by intravesical N-methyl-N-nitrosourea. Tumor cell implantation occurred in only 13 per cent of mice with bladder, whereas the presence an altered urothelial surface ther a 60 incidence tumors. has clinical implications but also offers model investigate modalities prevent tumor implantation.