Growth and growth hormone. II. A comparison of isolated growth-hormone deficiency and multiple pituitary-hormone deficiencies in 35 patients with idiopathic hypopituitary dwarfism.
作者： Harvey G. Goodman , Melvin M. Grumbach , Selna L. Kaplan
DOI: 10.1056/NEJM196801112780201
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摘要: Abstract Human growth hormone (HGH) deficiency was documented by radioimmunoassay in 35 patients — 16 with isolated HGH, 7 HGH and TSH, 4 ACTH, 8 TSH ACTH deficiencies. Of 15 deficiency, six had a previously normal PBI, suggesting progressive acquisition of tropic deficiency. Birth weight gestational age were usually multiple The onset variable, failure occurred before one year; continued at diminished rate. Hypoglycemia present 56 per cent those all Therapy associated pubertal development three age, the usefulness therapy differentiating hypopituitary dwarfs gonadotropin from whom delayed gonadal function is related to Dwarfism nonfamilial, s...
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