Chapter 11 Angiotensin II peptide hormone receptors: Structure/function correlates
作者： Kathryn Sandberg , Hong Ji
DOI: 10.1016/S1569-2582(97)80073-6
关键词:
摘要: Publisher Summary This chapter focuses on the structure/function correlates of cloned Angiotensin II (AT) receptors. A key step in understanding and manipulating RAS has arisen from cloning AT Polymorphisms AT-receptor genes may provide useful markers for genetic analysis patients with hypertension, and, fact, a polymorphic Mspl site was recently identified hAT1 gene. Transgenic models essential hypertension based receptors could facilitate gene function regulation vivo help elucidate involved clinical predisposition toward hypertension. In addition, role other conditions can now be examined by generation antibodies that permit tissue localization receptor quantitation.
sci-hub.se 参考文章(55)
Mohan K. Raizada, Cellular and Molecular Biology of the Renin-Angiotensin System ,(1993)
Roger M. Freidinger, Toward peptide receptor ligand drugs: Progress on nonpeptides Progress in drug research. ,vol. 40, pp. 33- 98 ,(1993) , 10.1007/978-3-0348-7147-1_4
S A Hjorth, H T Schambye, W J Greenlee, T W Schwartz, Identification of peptide binding residues in the extracellular domains of the AT1 receptor. Journal of Biological Chemistry. ,vol. 269, pp. 30953- 30959 ,(1994) , 10.1016/S0021-9258(18)47374-7
L Hunyady, M Bor, T Balla, K J Catt, IDENTIFICATION OF A CYTOPLASMIC SER-THR-LEU MOTIF THAT DETERMINES AGONIST-INDUCED INTERNALIZATION OF THE AT1 ANGIOTENSIN RECEPTOR Journal of Biological Chemistry. ,vol. 269, pp. 31378- 31382 ,(1994) , 10.1016/S0021-9258(18)31704-6
Y Kambayashi, S Bardhan, K Takahashi, S Tsuzuki, H Inui, T Hamakubo, T Inagami, Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition. Journal of Biological Chemistry. ,vol. 268, pp. 24543- 24546 ,(1993) , 10.1016/S0021-9258(19)74499-8
Signe Perlman, Hans T. Schambye, Ralph A. Rivero, William J. Greenlee, Siv A. Hjorth, Thue W. Schwartz, Non-peptide angiotensin agonist. Functional and molecular interaction with the AT1 receptor. Journal of Biological Chemistry. ,vol. 270, pp. 1493- 1496 ,(1995) , 10.1074/JBC.270.4.1493
K Sandberg, H Ji, A.J. Clark, H Shapira, K.J. Catt, Cloning and expression of a novel angiotensin II receptor subtype. Journal of Biological Chemistry. ,vol. 267, pp. 9455- 9458 ,(1992) , 10.1016/S0021-9258(19)50109-0
B Maigret, S Nouet, C Lombard, R Larguier, J Marie, J C Bonnafous, M P Joseph, Tyr292 in the seventh transmembrane domain of the AT1A angiotensin II receptor is essential for its coupling to phospholipase C. Journal of Biological Chemistry. ,vol. 269, pp. 20815- 20818 ,(1994) , 10.1016/S0021-9258(17)31893-8
S Murasawa, H Matsubara, M Urakami, M Inada, Regulatory elements that mediate expression of the gene for the angiotensin II type 1a receptor for the rat. Journal of Biological Chemistry. ,vol. 268, pp. 26996- 27003 ,(1993) , 10.1016/S0021-9258(19)74209-4
M Mukoyama, M Nakajima, M Horiuchi, H Sasamura, R E Pratt, V J Dzau, Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. Journal of Biological Chemistry. ,vol. 268, pp. 24539- 24542 ,(1993) , 10.1016/S0021-9258(19)74498-6